منابع مشابه
A Molotov cocktail
opamine and -synuclein are a toxic combination for neurons, say Jin Xu, Bruce Yankner (Children’s Hospital, Boston, Massachusetts) and colleagues. Aggregations of -synuclein are a hallmark of Parkinson’s disease (PD), and mutations in its gene are associated with familial forms of the disease. Yankner wanted to know why the protein is so toxic. When he overexpressed either wild-type or mutant f...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2002
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1577rr3